Brittle Bone Society

General information

Osteogenesis Imperfecta (OI), also known as "brittle bones", is a genetic bone condition characterised by fragile bones that break easily. A person is born with this condition and is affected throughout his or her lifetime. As well as frequent fractured bones, people with OI often have muscle weakness, hearing loss, fatigue, joint laxity, curved bones, scoliosis, blue sclerae, dentiogenenisis imperfecta (brittle teeth) and short stature. This occurs due to a defect in the formation of a fibrous tissue called collagen in the body.